Skip to product information
AbioSUS Single-Use Bioreactor

Applitech AbioSUS Single-Use Bioreactor

Available to order

The AbioSUS Single-Use Bioreactor is a comprehensive system comprising a stainless-steel bag holder (integrated with a TCU for temperature control), the AbioControl IDS.S controller, and the AbioBag culture bag.

Designed to replicate the conditions of traditional stirred-tank bioreactors, the AbioSUS ensures that process condi tions are comparable, enabling seamless transition between research, development, and production platforms.

Available in standard sizes of 50L, 200L, 500L, 1000L, and 2000L, with customization options, the AbioSUS supports a wide range of upstream cell culture applications for antibodies, vaccines, and cell/gene therapies.

Stainless-Steel Bag Holder

Dual-Jacket Design:

Both the bag holder and door feature a dual-jacketed structure connected to an integrated TCU, facilitating temperature control via water circulation within the jacket.

Temperature Range: 8°C - 40°C ±0.1°C (requires cooling water ≤8°C).

AbioBag Culture Bag:

The culture bag is mounted on a fixed frame and, once connected to the AbioSUS, forms a complete bioreactor system.

Constructed from 7-layer coextruded film.

Includes a dual-blade Marine impeller and dual bottom sparger ports.

Weighing Sensor Support Bracket:

During transport or long periods of non-use, the bracket absorbs load to prevent sensor damage.

During operation, the bracket is removed, allowing the C6-grade weighing system to monitor the culture weight directly.

Fixed Support Frame:

Secures the AbioBag culture bag, accommodates various filters, and organizes cables and tubing for enhanced durability and appearance.

Exhaust gas electric heating blanket.

Servo-driven stirring motor.

Door with Observation Window:

Large single-opening door simplifies bag replacement and features a transparent, graduated window for easy observation of the bag’s contents.

Dual-jacketed designed door for better temperature control.

Sensor Operation Area:

Mirrors the sensor interface arrangement of traditional stainless-steel bioreactors for familiar operation, ensuring full immersion of sensors in the culture medium while minimizing damage risk from proximity to the impeller. 

Supports traditional and single-usepH/DO sensors, with options fordual pH and dual DO configurations.


AbioControl IDS.S controller

• The controller's modular design offers flexible configurations suitable for a wide range of applications, supporting single-use bioreactors from 50L to 2000L.

• Includes five levels of operational access (View, Operator, Engineer, Supervisor, Administrator). Permissions manage ment ensures controlled production processes, with audit trail capabilities logging all operations.

• Equipped with an anti-mistouch and screen-lock function to secure the production process.

• Supports multiple control loops, including temperature, agita tion, pH, and DO. All process parameters are displayed, and process control strategies can be adjusted as needed.

• Flexible Cascade Control Loops allows switching based on control requirements to maintain parameter stability, ensuring experimental reproducibility and process consistency.

• Supports integration with third-party devices such as variable-speed pumps, mass flow controllers (MFCs), balances, and off-gas analyzers via 4-20mA or Modbus. It facilitates interaction with multiple control software systems and seamless data transfer.

• Customizable configurations to meet client-specific require ments.

• Equipped with a 24V DC UPS power supply to ensure the stability of the control and monitoring system and maintain continuous data recording.

• Enables quick switching of bottom aeration pathways via software.

• Designed to minimize footprint, saving valuable space.

.

You may also like